Jarrow Formulas Extra Strength Methyl Folate 400 mcg, Dietary Supplement for Cardiovascular and Neurological Health Support, 60 Vegie Capsules, 60 Day Supply

Health Benefits of Methyl Folate

Jarrow Formulas Extra Strength Methyl Folate delivers 400 mcg of Quatrefolic® methyl folate per capsule – a form prized for its stability and bioavailability. Adequate folate status may help support several aspects of health:

• May help support cardiovascular health – Methyl folate contributes to normal homocysteine metabolism, which supports heart health.
• May help support Neurological health – Folate is involved in neurotransmitter synthesis and nerve function.
• May help support proper cell division – Essential for rapid cell growth, such as during pregnancy and fetal development.
• May help reduce tiredness and fatigue – Folate contributes to normal energy metabolism.

These statements have not been evaluated by the Therapeutic Goods Administration. This product is not intended to diagnose, treat, or prevent any disease.

What Is Methyl Folate?

Methyl folate, also known as 5-methyltetrahydrofolate (5-MTHF), is the biologically active form of vitamin B9 (folate). Unlike synthetic folic acid, methyl folate is ready for immediate use by the body without needing conversion. This makes it particularly beneficial for individuals with genetic variations in the MTHFR gene, which can impair the conversion of folic acid to its active form.

This water-soluble vitamin plays a key role in methylation – a biochemical process essential for DNA synthesis, cell division, and homocysteine metabolism. By supporting these fundamental functions, methyl folate helps maintain overall health, especially in areas like cardiovascular and Neurological function.

Who Should Consider Taking Methyl Folate?

Methyl folate is especially beneficial for those who may have trouble converting folic acid to its active form. Common groups who may benefit include:

• Women planning pregnancy or who are pregnant – Adequate folate intake is crucial for neural tube development and healthy fetal growth.
• Individuals with MTHFR gene variants – These variations reduce the body’s ability to convert folic acid, so using pre-methylated folate may be more effective.
• Older adults – Absorption of natural folate may decrease with age, making supplementation helpful.
• Those with elevated homocysteine levels – Methyl folate may help support healthy homocysteine metabolism.
• Vegans and vegetarians – Dietary sources of folate can be limited, so a supplement may help ensure adequacy.

Always consult a qualified healthcare professional before starting any new supplement regimen.

Folic Acid vs. Methylfolate: Key Differences

Folic acid is the synthetic form of vitamin B9 commonly used in fortified foods and many supplements. To become active, folic acid must undergo a two-step conversion in the body, first to dihydrofolate (DHF) and then to 5-MTHF. This process relies on the MTHFR enzyme.

Methylfolate (5-MTHF) bypasses this conversion, directly providing the active cofactor. This is particularly advantageous for individuals with MTHFR polymorphisms, which affect an estimated 30–60% of the population. By choosing a methylated folate supplement, you ensure maximum absorption and immediate usability.

What Makes Jarrow Formulas Extra Strength Methyl Folate Unique?

This supplement uses Quatrefolic® methyl folate, a patented form known for its enhanced stability and bioavailability. Quatrefolic® is the glucosamine salt of 5-MTHF, which resists oxidation and provides reliable potency.

Jarrow Formulas is a trusted brand committed to quality. This product undergoes third-party testing to ensure purity and potency. It is also free from artificial colors, flavours, and preservatives.

Recommended Dosage and Usage

For adults, take one capsule daily with or without food, or as directed by your healthcare professional. Each bottle contains 60 capsules, providing a 60-day supply. The capsules are made from vegetable cellulose and are free from major allergens, including wheat, gluten, soy, dairy, eggs, fish, shellfish, peanuts, and tree nuts.

Jarrow Formulas Extra Strength Methyl Folate is also Non-GM, vegan-friendly, and suitable for those with dietary restrictions.

Frequently Asked Questions

Can I take methyl folate if I have an MTHFR mutation?

Yes. Methyl folate is the preferred form for individuals with MTHFR mutations, as it does not require the enzyme for activation.

Is this supplement safe during pregnancy?

Methyl folate is commonly recommended during pregnancy. However, consult your healthcare provider to determine the appropriate dosage for your needs.

How does methyl folate differ from folic acid?

Methyl folate is the active form, while folic acid requires conversion. Methyl folate may be more effective for those with genetic variations.

Always read the label and follow the directions for use. These statements have not been evaluated by the TGA. This product is not intended to diagnose, treat, or prevent any disease.