Jigsaw Health Activated B w/SRT - Sustained Release B-Complex, 120 Tablets

Benefits of Activated B w/SRT

If you're after a steady energy lift without the jitters or crash, this B-complex delivers. The active forms of B vitamins help convert food into usable fuel, so you feel more energised throughout the day. Mental clarity gets a boost too, thanks to B6, B9 and B12 supporting neurotransmitter production – think better focussed and a more balanced mood.

Your nervous system also benefits: B vitamins help maintain the protective myelin sheaths around nerves, which can ease feelings of stress. And because the Sustained Release Technology (SRT) metres out nutrients over several hours, you get a consistent supply instead of a spike. Plus, it supports cardiovascular health by keeping homocysteine levels in check and helps form healthy red blood cells for oxygen transport.

How to Take Activated B w/SRT

Take two tablets daily with food – swallow them whole, don't crush or chew. The sustained release works best when taken with a meal, which also helps reduce any chance of mild nausea. Most people prefer mornings or early afternoons, as B vitamins can be invigorating and might interfere with sleep if taken too late.

Avoid taking it at the same time as high-dose vitamin C or calcium supplements, as they can compete for absorption. Caffeine and alcohol can deplete B vitamins, so keep your intake consistent. As always, consult your health care professional before starting a new supplement, especially if you're pregnant, nursing, or on medication.

Key Ingredients & Active Forms

What sets Activated B w/SRT apart is its exclusive use of active, methylated forms. Here's a breakdown of each B vitamin and its bioavailable version:

• B1 (Thiamine) as Benfotiamine: A fat-soluble form of thiamine that may offer better absorption and retention than standard thiamine HCl.
• B2 (Riboflavin) as Riboflavin 5'-Phosphate (R-5-P): The active coenzyme form, ready for energy production without needing conversion.
• B3 (Niacin) as Inositol Hexanicotinate: A flush-free form of niacin that supports circulation and lipid metabolism without the uncomfortable flushing.
• B5 (Pantothenic Acid) as Calcium Pantothenate: The standard form, essential for coenzyme A synthesis and fatty acid metabolism.
• B6 (Pyridoxine) as Pyridoxal-5-Phosphate (P-5-P): The active form, particularly beneficial for individuals with MTHFR genetic variations who struggle to convert standard B6.
• B7 (Biotin) as d-Biotin: The naturally occurring form, critical for hair, skin, and nail health.
• B9 (Folate) as L-Methylfolate (Metafolin®): The active, methylated form of folate that can be used directly by the body, especially important for those with MTHFR mutations.
• B12 (Cobalamin) as Methylcobalamin: The active coenzyme form, superior to cyanocobalamin for neurological support and methylation.

Each ingredient is carefully dosed to meet or exceed daily values, with B12 at 500 mcg per serving. The sustained release matrix ensures these active nutrients are delivered gradually, optimising absorption and minimising waste.

How to Choose the Right B-Complex

Not all B-complex supplements are created equal. When evaluating options, consider the form of each B vitamin. Cheap formulae often rely on folic acid and cyanocobalamin, which require conversion steps that some people cannot perform efficiently. Active forms like methylfolate and methylcobalamin are preferable, especially for individuals with MTHFR polymorphisms.

Delivery method also matters. Standard tablets can cause a rapid spike in B vitamin levels, leading to bright yellow urine as excess is excreted. Sustained release technology, like Jigsaw's SRT, provides a steady supply over 6–8 hours, improving retention and reducing waste. If you have a sensitive stomach or liver concerns, active forms are gentler because they don't require hepatic conversion.

Other factors include allergen information: Activated B w/SRT is gluten-free, vegetarian-friendly, and contains no artificial colours or preservatives. Always check for third-party testing or quality seals. Jigsaw Health is a reputable brand founded in 2005 with a focussed on absorbable, effective supplements. Reading customer feedback can also provide insight into real world experiences – many users mention improved energy levels and mental clarity without side effects.

Side Effects & Interactions

B-complex supplements are generally well-tolerated, but some individuals may experience mild side effects. The most common is bright yellow urine, which is harmless and results from excess riboflavin being excreted – this is less pronounced with sustained release. Some people report mild gastrointestinal upset, headache, or skin flushing (though the flush-free niacin form minimises this).

High doses of B6 (pyridoxine) taken long-term have been linked to nerve toxicity, but the amount in Activated B w/SRT is within safe limits. Always stay within the recommended serving size. Interactions with medications are possible: B6 can reduce the effectiveness of certain epilepsy drugs like phenytoin, while B9 (folate) can mask a B12 deficiency in those with pernicious anaemia. If you take blood thinners, chemotherapy drugs, or are on a restricted diet, discuss with your doctor before use.

Always read the label and follow directions for use.

Frequently Asked Questions

Is this product suitable for vegans? Yes, the ingredients and excipients are vegan-friendly. The tablets are made without animal products.

Does it contain any caffeine or stimulants? No. The energy support comes solely from B vitamins, not added stimulants.

Why is the urine sometimes yellow? High-dose riboflavin (B2) is water-soluble and can cause a harmless bright yellow discolouration. With SRT, the effect is less pronounced.

Can I take this if I have an MTHFR mutation? Absolutely. This formula uses methylated folate and B12, which are ideal for individuals with MTHFR variants who cannot convert synthetic forms.

How long does one bottle last? With 120 tablets and a serving of two tablets per day, a bottle provides a 60-day supply.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, , or prevent any disease.

What is B-Complex?

B-complex supplements deliver all eight essential B vitamins – B1 (thiamine), B2 (riboflavin), B3 (niacin), B5 (pantothenic acid), B6 (pyridoxine), B7 (biotin), B9 (folate), and B12 (cobalamin). These water-soluble vitamins work synergistically to convert food into cellular energy, support neurotransmitter function, and maintain healthy red blood cells. Unlike generic B-complex formulae that use inexpensive synthetic forms requiring liver conversion, Jigsaw Health's Activated B w/SRT features the active, bioavailable versions of each B vitamin. This means your body can use them immediately, bypassing the need for enzymatic conversion. The result is more efficient absorption and a gentler experience for your liver.

Activated B w/SRT also incorporates a proprietary Sustained Release Technology (SRT), which metres out the B vitamins gradually over several hours. This steady release mimics how whole foods deliver nutrients and helps maintain consistent blood levels, avoiding the spikes and crashes often associated with immediate-release supplements. Whether you're combating daily fatigue, supporting mental clarity, or promoting nervous system health, Activated B w/SRT offers a science-backed approach to B-complex supplementation.